The reason why the Cortef suspension failed is because, as a chemical compound, hydrocortisone  is not completely water soluble....in other words, it does not completely dissolve in water.  So, when a liquid form of the medication is made, an emulsifying agent....which holds everything together....is needed.  With the Cortef suspension,  I think it was actually the emulsifying agent that failed.  As a result, the medication often settled at the bottom of the bottle or stuck to the sides, resulting in kids not getting their full dose.

There is the POTENTIAL for that to happen with any hydrocortisone liquid....it is part and parcel of the drug’s inherent biochemical properties.  Whether or not it will, when a particular pharmacy makes it specially, who’s to say.    But, the possibility is there.....that is why many doctors want to stay away it.   It could very well be fine, but neither is there any guarantee of quality assurance, unlike with commercial products that have to meet FDA approval.