AnneThis is wonderful news, Kathy PLEASE keep us posted. I am sorry to hear about your son, it must have been hard for you both. I am sure if the hydrocortisone is delivers in this method slowly and to mimic the circadian rhythm, there will be less side effects. How fantastic, less weight gain, better growth, less mood swings. I applaud Dr Hindmarsh, please thank him from us parents this is what we need. I cannot wait to read this paper. Thank youAnne