My daughter slowing fell off the growth charts and was not growing or gaining weight. Even when we lowered her dose she didn’t grow. We changed the schedule of meds and she began to grow. We followed the circadium rhythm method of dosing and it worked wonders. Yes, we have to get up at 3am but it has been well worth. There are some great articles out there about how and why this schedule works more efficiently to bring levels in good control while not suppressing the growth hormone at night. It has worked wonders for my daughter she is in the 75% in height and weight now. If you are interested I can give more info. Also look in the archives. Good luck, JUlia