For those who are having growth issues and are not doing circadian dosing I would like to share my experience.  About 9 months ago, my son’s doctor suggested that I should give him a dose of cortef before bedtime so his bone age won’t advance.  I tried that and for the next 2 visits no growth.  I switched back to 4 PM, 3 AM and upon waking and bingo he grew 3/4 " the last 3 months.  This is about the third time that I have experimented with his dosing and everytime I give him something before bedtime he doesn’t grow.   The doctor may even be starting to believe me.  And it also takes about 3 months for growth to start again after I change the timing.