There is a connection to not handling stress because the normal responsis by a healthy body is a series of chemical releases that a person with CAH may not make and if the chain of events does not release the proper chemical it may realse something eles in its place . They explained to us that when Mike’s body was not making Cortisone it thought it could and worked harder but instead of making cortisone it OVER produced free testosterone not only effecting fertility but causing him to loose control and rage!