I too have been wondering the samething. I have also been where you are Dilini. I have had severl up and down episodes in my life concerning depression. So has my mother, grandmother and sisters. Could it be because we are all carriers. I still search for a reason for all of our confusion in our lives. There has to be a link somewhere. Right now I am on celexia. So far I have not had any weight gain problems. It works really well. I hope you find something that works for you. I do notice a big change in my personality when I forget to take it. It feels like my whole world is falling apart. It has worked wonders for me. I can handle every thing alittle bit better especially the stress. You can say taking an antidepressent saved my life. I can now handle my sons cah better. I don’t have the racing thought like I used to. I would never open up about this before, but on this board I don’t feel alone now. I know now that I am not the only person going through this too. I just want an answer too!!!