We dose at (approximate times, sometimes a bit before, sometimes a bit after) 6.30 am, 3pm (usually 3.15 on school days when she gets home from school) and 10.30 pm. If I am really tired, on occasion the 10.30 pm dose might be 9.30 pm. With this dosing there is no need for meds at school which we find works well. Having said all of that, we are really no that exact with times, as I said they can be a bit before or after the times I have stated.Jenni