What time do you give the morning dose? My son had the same problem and we started giving his morning dose at 4:30am. We were able to cut his cortef dose almost in half! He was taking 37 1/2 mg and was still off the charts. they reduced his dosage to 20mg and the results were amazing. We still dose after school and at bedtime. It might be worth a shot just to try this minor change.Cheryl