No we have never tried circadian dosing.  My endo initially only had my daughter on twice a day dosing until about 31/2 then I switched it to 3 times because she was having really bad fits at preschool and I thought it might have something to do with her dosing.  This didn’t seem to help though.  What times to you give the meds and do you have any problems with the night dosing.  My daughter is a very heavy sleeper, we still even have trouble with bedwetting on occasion because of it. 

How has this helped you son, example?

Thanks for the input