Hi Le,

The article does say that the numbers for people with CAH can be somewhat higher than those given in the chart and still be considered "acceptable"(just wanted to be sure you saw that.)

As for how 17-ohp can be low, when 17-KS are high: As you know, a blood 17-ohp tells you what the number is at a specific point in time. So it can be influenced by the events that directly preceded the blood draw (medication, stress, etc.) In contrast, the 17-KS gives values averaged over 24 hours, so gives you a better idea of what happens over the course of an entire day. So...a low 17-ohp (if obtained after medication), but highish 17-ks, could signify that control is good for a period of time after taking medication, but then escapse for a period of time when the medication wears off . (Not saying this is what is happening with your child, but just giving an example.)

Frustratingly, test results do often conflict with each other, and do not always seem logical. When that happens, you almost have to be like a Sherlock Holmes, trying to figure out what the "evidence" is telling you. However, I think it’s good to keep in mind that test results are just one piece of the puzzle. In my opinion, what is just as important, if not more so, is how your child looks, feels, and acts in "real" life.