My girls (8 & 10) are both on 6 hour dosing.  7am, 1pm, 7pm and 1am.  We did not notice any changes like this with the girls when we switched, if anything, they slept better.  They never wake up for their 1 am dose.  I would talk to your endo and ask about this.  There could be other things going on to cause the lack of sleep. 

I recommend circadian or 6 hour dosing if you have trouble with weight and growth issues or control issues.  Since we have switched to this method, the girls are nearly perfect in their levels.  If you have any questions, please feel free to ask me.

Blessings,

Tonia