http://www.forbes.com/business/feeds/afx/2006/12/06/afx3231549.htmlbraydensmomlink above one of several news articles
http://www.phoqus.com/fdosage.html <--- link from the company
It sounds to me like a logical system, but that’s why we have clinical studies. My "regular person - not a doctor or scientist" understanding is that any research of this nature must go through many steps before it ever gets to the stage where it can be tested on the very people the doctors hope it will help.
Research studies aren’t for everyone. SOMEBODY has to "go first" so to speak for any type of research to move forward.
A person with CAH is already on one form or another of a steroid: hydrocortisone, dexamethasone, prednisone. It’s not a matter of taking your meds or not. The question for this study will be; Will a slow release formulation work effectively? One of the reasons this would be a question is because the pill will NOT just sit in the human stomach. Like anything else swallowed, the pill would go through the entire digestive tract, slowly being digested along the way. My understanding is that this formulation will (we hope) effectively release (with the digestion process) smaller amounts of steroid over longer amounts of time. The body would get the same required dose but over the more desired spread of time. For those parents now getting up or staying up until 2:00AM to dose their child according to the circadian rhythm... this research is a VERY good thing.
I myself look forward to more information on the progress of Qtrol and my son has already eagerly raised his hand to participate in the research.Susan