I don’t kknow for sure but I think not. I have many food/drug allergies. Once when I had a very bad reaction I was trying to figure out what might have caused it. I asked my allergist if it could have been the cortef or florinef. He quickly said no. In fact hydrocortisone is give when you have an allergic reaction. I go into anaphelactic shock from stings. Every time they put me on hydrocortisone for a week to prevent a reoccurance which can happen sometimes with bad reactions. I wonder if it is something else causing the rash and it is a coincidence? Good luck! Julia