Hi, in respect to the original question.
The only difference in any of the forms of replacement corticosteroids is the half life of the drug. They are all chemically the same, only the length (or time) of action is different. It's all about getting the balance of the corticosteroid levels in the blood to be as constant as possible over the 24hr period as possible.
Any ill effects from a change in the particular steroid would be a result of the levels being too high or too low. This will depend on how fast the body is metabolizing, and the bodies demand for the steroid throughout the day. If the endocrinologist has got the correct doses worked out, there shouldnt be a problem. However, having said that, some of the replacement steroid types just dont seem to be able to meet the unique requirements of the individual and it takes a lot of "choping & changing" to get it right.
Andy.RN. Bng. Grad.Dip. (Emergency). and Father of two children with CAH.
South Australia.
