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As Rick said - as long as your well monitored you hypothetically shouldn't have any problems. I did however. I've always been the biggest in my family - my sister (lol, also a millie!) is virtually anorexic....but you get that in all families.
Ummm, well the whole steroid and weight thing can be easily controlled (to a degree.) When I was 15 or something I ended up being the first patient my doctor saw loose as much weight as I did - whilst still heavily medicated. Ironically because that happened, my dose went down and I no longer had to be oversuppressed to control all my hormone levels. So since I am not taking as much as I used to, I suppose that its relatively easy to find some sort of healthy compromise.