Congenital Adrenal Hyperplasia

ATTENTION MEDIA & OTHERS SEEKING INTERVIEWS! 
If you represent a media company, are a student writing a report or anyone interested in interviewing our visitors, please seek permission (see email address at the bottom of the page) before posting your requests or emailing solicitations for any talk show, magazine, thesis, census or other interview on any message board on this site. If not, your posts WILL be removed. Please respect the privacy of our members.

    Return to Page 19Post reply       


re: re: re: re: (to Kat) crazy labs
Apr. 27th, 2007   3:15pm
I got this from the wikipedia article on licorice-

Large doses of glycyrrhizinic acid and glycyrrhetinic acid in liquorice extract can lead to hypokalemia and serious increases in blood pressure, a syndrome known as apparent mineralocorticoid excess. These side effects stem from the inhibition of the enzyme 11β-hydroxysteroid dehydrogenase (type 2) and subsequent increase in activity of cortisol on the kidney. 11β-hydroxysteroid dehydrogenase normally inactivates cortisol in the kidney; thus, liquorice's inhibition of this enzyme makes the concentration of cortisol appear to increase. Cortisol acts at the same receptor as the hormone aldosterone in the kidney and the effects mimic aldosterone excess,

http://en.wikipedia.org/wiki/Licorice

So if your daughter has a natural deficiency of 11β-hydroxysteroid dehydrogenase (type 2), then it would the same as if she was eating licorice. Or if she had kidney problems. But she could have CAH and still have high aldosterone/cortisol.

bee girl




    Return to Page 19Post reply       


This Thread





- Post a reply - 

page processed in 0.10324883461 seconds
Rare Disease Search Engine, Homeschool Sites, Online Homeschool, Online Income, Ethical Adsense, Creative writing, Family Web Hosting, Christian Radio, Tulsa Parks