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I'm taking 5 mg of prednisone now and my endo always to let her know if I get pregnant because she'll have to take me off the prednisone b/c it can cross into the barrier and if I'm preg. with a girl it can masculinize her. I don't know, maybe it will be different for you if you'd have to take a lower dose of prednisone. But I would definitely ask my endo about it. Maybe both our endos are lying lol.