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After many years of symptoms, such as fatigue, anxiety, getting more coarse hair on face, acne on face and upper body, etc., I found this site. I just received a lab that says my DHEA-S is 647 (0 - 240?). It had been normal for the last few years, as I have had quite an endo work-up over the last few years. I only have one ovary, but it, for years, has only had one cyst, at 1 cm. All my life, w/o birth control, I had clockwork periods, up until a few years ago, now about 1 period a year. Does the high DHEA-S suggest LOCAH might be a possibility? I have also had upper abdominal bloating really bad for the last few years, and now wonder if the CT scans did not adequately show adrenal size. By the way, a year ago they were Ct my abdomen to watch a 7 mm adenoma on my adrenal. My cortisol has never showed up low. Thanks for any input on the DHEA!