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re: re: SWCAH vs. No adrenals Mar. 10th, 2008 8:33am
After an adrenalectomy lower doses of glucocorticoids can be used to maintain. Usually higher doses of cortisteriods are used in CAH patients to lower the levels of androgens as compared to those who just need cortisteriods to replace and maintain. The only arguments of having a complete bilateral adrenalectomy is that the adrenal medulla will be lost as well as the adrenal cortex. Adrenaline (epinephrine) is made in the medulla. With the inability to make even a proportion of epinephrine, this can make you vulnerable in stressful situations. But with CAH individuals you already have an impaired medulla as compared to others.
(information can be found in CAH: a parents guide)